postheadericon & ECM Growth Within Ensuing Haematoma

Below this paragraph you will find information related to the subject/method of Autologous Blood Transfer for Acne Scar Revision. I originally wrote this text in the Scarless Healing thread. Nonetheless, I have since decided to include it here as a partial introduction to this new thread. If you want to cut to the chase read the second half of the text, wherein I briefly discuss the use of blood as a filler substance for acne scar depressions. I also introduce the histological mechanisms by which blood injected into said depression(s) can stimulate collagen formation and cellular differentiation from 'Peripheral Blood Stem Cells' that are present in minute quantities within your blood serum. Further still, the endogeneic growth factor proteins, amino acids, platelets and white cells present within blood all play a direct role in the healing process. Finally the resulting haematoma at the intra-dermal site of injection creates the conditions necessary for collagen deposition and growth. Indeed blood contains fibrocytes that are important for the production of Type I Collagen.

Below is the text I wrote in the Scarless Healing thread:

I've been getting quite a few private messages from acne.org members who are in a lot of pain and desperation. I am happy to talk to you, and I always try to answer your questions in detail. I want you to know that I'm here to help in my own small way, but so far I've tried to stay away from encouraging people to do something drastic. That said, due to the fact that medical services are exceptionally expensive and that many if not most doctors are selfish or at the very least emotionally detached to the point of losing the drive and inspiration to attempt perfection whilst working on your scars, I have decided I am going to try and give you more knowledge in the hope that you will find a way to make it work for you.

I will suggest a freely available and in fact easily accessible autologous filler substance that has been shown to have efficacy in treating depressed acne scars. Based on the information that I provide, you may potentially then agree that this filler can be easily transplanted/injected into a recipient site by just about anyone with a steady hand, discipline and adherence to a maximally sterile (aka: sterilized skin, syringe, etc), yet simple procedural methodology. This suggestion will contradict what most doctors tell you, because for one reason or another many of them have become automated appendages of the money hungry corporations/producers of synthetic fillers. So I say this at my own risk, but then again, no one here knows my name. Likewise, this information and the given method for acne scar revision is yours to use according to your own free will and at your own personal risk. After all, if one is not careful, even the safest procedure can become a hazard to your health.

Obviously there are many fillers, most of them synthetic and or composed of foreign tissue, so they are not only expensive but also dangerous. Yes they help, but at times they also harm. You need a doctor that is like an artist, full of passion and expertise, who is willing to work with you for hours upon hours, week after week, until something near perfection can be achieved. Unfortunately this will cost you a small fortune. Sometimes, you may opt to go to a relatively poor country where the same service will not impact your bank account to the same degree. Even so, it is not easy to find the surgical talant, kind heart and perfection oriented intellect all combined into one human 'medical practioner's package.

I don't know if you've heard of this, but autologous substances when used correctly can provide permanence in tissue augmentation. You all likely know of autologous fat injection and autologous collagen injection. However, you do not have access to these materials. It would be very dangerous for anyone to attempt to harvest/isolate either of these substances from themselves. So you are left with only one option and that is to go to a doctor in your area, who will charge you a lot of money only to give you an imperfect service.

Now think of your days in high school math class and try to recall the Bell Curve. Split it up according to standard deviations. The horizontal axis of this Bell Curve represents the cosmetic/surgical skills of doctors. Any career, and indeed anyone regardless of their educational background, will in one way or another fall somewhere on this curve. Doctors included! From a statistical standpoint then, 50% of doctors are below average in their skills, while only those beyond 1.5 to 2.0 standard deviations on the right side of the curve's average can be considered to have good skills. The top 2.5% are those that are considered outstanding. That's 1 in 40… You have to do your homework to find these bright lights in a largely dark world.

Generally the 1 in 40 doctors will charge you more for their unusual abilities. This however is not always the case. Again, these doctors, including the artistic geniuses ( the 1 in 100 factor ) are also present in poor countries. If you are from a wealthy area of the world, you may just be able to afford them and their supreme abilities. But even so, there is the issue of travel, the difference in medical culture, etc that make this less practical. Also, many of the supreme doctors might be great with their hands, but again could potentially turn out to be indifferent and incapable of accepting their own fallacy should problems arise. Those that think they are gods sometimes make the biggest mistakes!

OK, so here's the reality.

Your bone marrow tissue mixed with your blood can be injected into your acne scars. I don't know if it has been done, but cardiologists have been experimenting with this for some time now. Scar tissue seems to get rebuilt in such experiments and healthy heart function returns often within weeks of injection into the scarred areas of the heart muscle.

The problem with this is that again you will have to go to a foremost expert who is willing to try this. The costs involved would be through the roof. Further still, what would the results be? I believe quite good, but I don't have proof as I have not done this procedure myself. That said, it works in the heart experiments because your bone marrow contains stem cells. It also contains a host of other things that will give recipient cells a myriad of regeneration stimulating signals.

What about your blood? Yes, your blood can be injected into your acne scars. This is where I can get into a lot of trouble, but then again my identity is secure. Haha! Or at least I happen to think so, thus I am enjoying a feeling of security that could potentially be a case of 'ignorance is bliss'… Oh well!

What many of you probably didn't know because some doctors forgot to tell you is that your own blood injected into scar tissue can cause a haematoma that in turn perpetuates collagen formation in that exact area.

Here's a quote:

“In this study, we explored the possibility of blood injection as a means of augmenting the labrum's contribution to the glenoid concavity. Tissue augmentation by injection of materials has become a well-established procedure in the fields of dermatologie and cosmetic surgery.18-21 It has also been advocated, in view of its minimal invasiveness and morbidity, as a primary treatment for velopharyngeal incompetence22 and dysphonia.23 Materials used for injection have included bovine collagen, homologous collagen, hyaluronic acid gel, and autologous fat. The use of autologous blood to augment atrophie acne scars has also been reported to be effective and has been postulated to have a long-lasting effect by inducing collagen formation in the resulting haematoma.24″

Here's another quote from a different source:

“Blood transfer is a unique method of injecting one's own blood into a depressed acne scar. For deeper scars, blood can be injected to correct the skin deficit, which then induces collagen production in the area to produce a medium to long-term improvement. For more superficial scars, a smaller amount of blood is injected superficially into the scar, and then a vascular laser such as the Gemini laser is used to fire into the acne scar containing blood. The laser is attracted specifically to the blood, and this induces a stimulation of collagen in the scar which helps to raise the skin to a more even level.”

Is this as effective as other fillers? I am not certain, since a comparative study must be performed in order to ascertain the relative efficacy of such a procedure. However, my analysis and consequent application of logic as based on sound scientific principles leads me to believe that it could very well be just as effective as those “other” fillers that claim to stimulate collagen formation, yet end up costing you more than your car is worth. OK, maybe I'm exaggerating, but you get the point.

Research the composition of blood and the way in which it functions to gain further insight into what this procedure could mean for you. Do the searches and come to your own conclusions. You deserve the power of information. This is information that can then be transformed by your minds into knowledge… and I may be going on a limb here, but perhaps you have more knowledge about acne scars then 99% of doctors out there. Remember the Bell Curve!

Do what you want with this knowledge, but remember:

a) blood contains 'peripheral blood stem cells' b) blood contains many other cells (neutrophils, monocytes, etc) that are vital for repair, including proteins for cellular communication, fibroblast regulation, etc c) blood is easy to extract (You know the drill…) d) it's yours after all, so it's free and your veins are not all that difficult to get to (Oh boy!)

Some might want to 'biblically' stone me to death for saying this. But since joining acne.org I can clearly see that people are doing all kinds of dangerous things to themselves precisely because of the pain and desperation present within their/our suffering souls. So I finally decided I might just lose my professional sanity here by sharing this piece of information…

Again, I suggest you discuss this with a doctor who wants to truly help you… I also hope he's up there in the skills we discussed. Note, one must sterilize the skin before injection and one must inject very soon after blood extraction, because you don't want cells within the blood to die. Injection should occur at differing angles depending on the scar present and sometimes at slightly different intra-dermal levels.

OK, there it was! I'm tired now… I feel good and bad all at once. It takes a great deal of time and effort for me to compose these messages and articulate them in a way that is beneficial for your/our cause. I do my best to express myself in an understandable fashion as English is not my first language. Anyway, whatever your opinion may be, base it on knowledge and understand that this is my way of helping you… Even if there may be member-to-member disagreements on moral, ethical and/or professional levels, I believe this is the way in which I can help.

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